1-(4-Bromo-3-methylphenyl)ethanol → 1-[4-(1-Hydroxy-ethyl)-2-methyl-phenyl]-ethanone

HRID 1425756노트

반응식

HRID 1425756 반응식
[OH:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9](=[O:11])[CH3:10])=[C:5]([CH3:12])[CH:4]=1.Br[C:14]1C=CC(C(O)C)=CC=1C>>[OH:1][CH:2]([C:3]1[CH:8]=[CH:7][C:6]([C:9](=[O:11])[CH3:10])=[C:5]([CH3:12])[CH:4]=1)[CH3:14]

참가 물질

3

반응물 2

HCID 790169431-(4-Bromo-3-methylphenyl)ethanolHCID 866955361-(4-Hydroxymethyl-2-methyl-phenyl)-ethanone

생성물 1

HCID 866955571-[4-(1-Hydroxy-ethyl)-2-methyl-phenyl]-ethanone수율 49%

실험 절차

1-[4-(1-Hydroxy-ethyl)-2-methyl-phenyl]-ethanone is prepared following preparation 1a employing 1-(4-bromo-3-methyl-phenyl)-ethanol instead of (4-iodo-3-methyl-phenyl)methanol.

출처 및 근거

ORD 기록
ord-701be293fc5e454bb44615eaca7db368
출처 데이터셋
uspto-grants-2015_01
특허 번호
US08933079B2

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