Dimethylamine → HCID 67997831, 화합물

반응식

[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([C:11]([OH:13])=O)[CH2:10][CH2:9]2)=[N:6][CH:7]=1.[CH3:14][NH:15][CH3:16]>>[CH3:14][N:15]([CH3:16])[C:11]([C:8]1([C:5]2[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][N:6]=2)[CH2:10][CH2:9]1)=[O:13]

참가 물질

반응물 2

HCID 674Dimethylamine

HCID 694761531-(5-Bromopyridin-2-YL)cyclopropanecarboxylic acid

생성물 1

HCID 67997831HCID 67997831, 화합물

실험 절차

The title compound was prepared from 1-(5-bromo-pyridin-2-yl)-cyclopropanecarboxylic acid and dimethylamine (2 mol/L in tetrahydrofuran) following a procedure analogous to that described in Step 2 for Intermediate 5. Yield: quantitative; LC (method 1): tR=1.65 min; Mass spectrum (ESI+): m/z=269/271 (Br) [M+H]+.

출처 및 근거

ORD 기록: ord-4b3d0b42d9494333b07102517cf9d371
출처 데이터셋: uspto-grants-2015_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08933072B2

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