1-Ethynyl-4-methoxybenzene → 2-tert-Butyl-6-(4-methoxy-phenylethynyl)-pyrazolo[1,5-a]pyrimidine

HRID 1426200

반응식

HRID 1426200 반응식
Br[C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:10]=2)[CH:7]=1.[C:15]([C:17]1[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=1)#[CH:16]>>[C:11]([C:9]1[CH:10]=[C:5]2[N:4]=[CH:3][C:2]([C:16]#[C:15][C:17]3[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=3)=[CH:7][N:6]2[N:8]=1)([CH3:14])([CH3:13])[CH3:12]

참가 물질

3

반응물 2

HCID 2510201-Ethynyl-4-methoxybenzeneHCID 583166976-Bromo-2-tert-butylpyrazolo[1,5-a]pyrimidine

생성물 1

HCID 532472012-tert-Butyl-6-(4-methoxy-phenylethynyl)-pyrazolo[1,5-a]pyrimidine

실험 절차

The title compound, yellow solid, MS: m/e=306.2 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-tert-butyl-pyrazolo[1,5-a]pyrimidine (example 9, step 1) and 1-ethynyl-4-methoxybenzene.

출처 및 근거

ORD 기록
ord-1fd6229a21624f098b4e8950fa7754d6
출처 데이터셋
uspto-grants-2015_01
특허 번호
US08933094B2

연결된 노트

불러오는 중…