2-Pyridinamine, 5-iodo- → 5-(2-tert-Butyl-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)-pyridin-2-ylamine
반응식
[C:1]([C:5]1[CH:15]=[C:8]2[N:9]=[CH:10][C:11]([C:13]#[CH:14])=[CH:12][N:7]2[N:6]=1)([CH3:4])([CH3:3])[CH3:2].I[C:17]1[CH:18]=[CH:19][C:20]([NH2:23])=[N:21][CH:22]=1>>[C:1]([C:5]1[CH:15]=[C:8]2[N:9]=[CH:10][C:11]([C:13]#[C:14][C:17]3[CH:18]=[CH:19][C:20]([NH2:23])=[N:21][CH:22]=3)=[CH:12][N:7]2[N:6]=1)([CH3:4])([CH3:3])[CH3:2]참가 물질
3
실험 절차
The title compound, off white solid, MS: m/e=292.1 (M+H+), can be prepared in accordance with the general method of example 1 from 2-tert-butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidine (example 21, step 2) and 5-iodopyridin-2-amine.
출처 및 근거
- ORD 기록
- ord-1cb737a1345743c6af303c11a55794cc
- 출처 데이터셋
- uspto-grants-2015_01
- 특허 번호
- US08933094B2
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