Propargylamine → HCID 86707259, 화합물

HRID 1427746노트

반응식

[S:1]1[CH2:5][CH2:4][C@H:3]([CH2:6][CH2:7][CH2:8][CH2:9][C:10]([OH:12])=O)[S:2]1.[CH2:13]([NH2:16])[C:14]#[CH:15]>>[S:1]1[CH2:5][CH2:4][C@H:3]([CH2:6][CH2:7][CH2:8][CH2:9][C:10]([NH:16][CH2:13][C:14]#[CH:15])=[O:12])[S:2]1

참가 물질

반응물 2

HCID 239041Propargylamine

HCID 445125(S)-lipoic acid

생성물 1

HCID 86707259HCID 86707259, 화합물

실험 절차

In amide coupling reaction (as shown in Scheme 10), (S)-5-(1,2-dithiolan-3-yl)pentanoic acid (11) and prop-2-yn-1-amine perform coupling reaction to form (S)-5-(1,2-dithiolan-3-yl)-N-(prop-2-ynyl)pentanamide (12).

후처리

customreaction

출처 및 근거

ORD 기록: ord-dc1944ff31fe47419c4582a9b88fb640
출처 데이터셋: uspto-grants-2015_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08933273B2

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