Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
L-(+)-Cysteine → Isopenicillin N
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | L-(+)-Cysteine | HCID 5862 | — |
| 반응물 | L-Valine | HCID 6287 | — |
| 반응물 | Penicillin G Potassium | HCID 23664709 | — |
| 생성물 | Isopenicillin N | HCID 440723 | — |
반응 단계
The first two steps in the biosynthesis of penicillin in P. chrysogenum are the condensation of the three amino acids L-5-amino-5-carboxypentanoic acid (L-α-aminoadipic acid) (A), L-cysteine (C) and L-valine (V) into the tripeptide LLD-ACV, followed by cyclization of this tripeptide to form isopenicillin N. This compound contains the typical β-lactam structure.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05726032 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-3bb66da6f37b43aebd4a5504e234b1f4 |
| 출처 메모 | uspto-grants-1998_03 |