2-Amino-4,6-dichloropyrimidine → 6-Chloro-N4-[3,5-difluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]pyrimidine-2,4-diamine

HRID 143071

반응식

HRID 143071 반응식
[Cl:20][c:21]1[n:22][c:23]([NH2:28])[n:24][c:25]([Cl:27])[cH:26]1.[F:1][c:2]1[cH:3][c:4]([NH2:19])[cH:5][c:6]([F:18])[c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[nH:15][cH:16][cH:17]2>>[F:1][c:2]1[cH:3][c:4]([NH:19][c:25]2[n:24][c:23]([NH2:28])[n:22][c:21]([Cl:20])[cH:26]2)[cH:5][c:6]([F:18])[c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[nH:15][cH:16][cH:17]2

참가 물질

3

반응물 2

HCID 655222-Amino-4,6-dichloropyrimidineHCID 179792873,5-difluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)aniline

생성물 1

HCID 587333666-Chloro-N4-[3,5-difluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]pyrimidine-2,4-diamine

출처 및 근거

ORD 기록
ord-fa37692d3a444d07b824b26d91a0d593
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

연결된 노트

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