6-Aminopicolinonitrile → HCID 86708593, 화합물

HRID 1430896노트

반응식

HRID 1430896 반응식
[CH:1]1([N:4](CC2C=CC(OC)=CC=2)[C:5]2[C:10]3=[N:11][CH:12]=[C:13]([C:14]#[N:15])[N:9]3[N:8]=[C:7](S(C)(=O)=O)[N:6]=2)[CH2:3][CH2:2]1.[NH2:29][C:30]1[N:35]=[C:34]([C:36]#[N:37])[CH:33]=[CH:32][CH:31]=1>>[C:36]([C:34]1[N:35]=[C:30]([NH:29][C:7]2[N:6]=[C:5]([NH:4][CH:1]3[CH2:2][CH2:3]3)[C:10]3=[N:11][CH:12]=[C:13]([C:14]#[N:15])[N:9]3[N:8]=2)[CH:31]=[CH:32][CH:33]=1)#[N:37]

참가 물질

3

반응물 2

HCID 5642986-AminopicolinonitrileHCID 86708519HCID 86708519, 화합물

생성물 1

HCID 86708593HCID 86708593, 화합물

실험 절차

The compound was prepared starting from 4-(cyclopropyl(4-methoxybenzyl)amino)-2-(methylsulfonyl)imidazo[2,1-f][1,2,4]triazine-7-carbonitrile (50 mg, 0.125 mmol) and 6-aminopicolinonitrile (17.94 mg, 0.151 mmol) using the procedure for Example 1E. Material was carried forward into the next step as is.

후처리

  1. customThe compound was prepared

출처 및 근거

ORD 기록
ord-8cf7a8cf42df4067a9e7f790cd0b253d
출처 데이터셋
uspto-grants-2015_01
특허 번호
US08940736B2

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