Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzaldehyde → 3-[(5-Fluoro-3-methyl-1H-indol-2-yl)-phenyl-methyl]-4-hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzaldehyde | HCID 240 | — |
| 반응물 | 5-Fluoro-3-methyl-1H-indole | HCID 22351503 | — |
| 반응물 | 4-Hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one | HCID 56604111 | — |
| 생성물 | 3-[(5-Fluoro-3-methyl-1H-indol-2-yl)-phenyl-methyl]-4-hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one | HCID 57933431 | — |
반응 단계
Using general procedure C, 4-hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one (Lit. 11) was reacted with benzaldehyde and 5-fluoro-3-methyl-1H-indole to give the title compound as a yellow solid. MS: 377.1 ([M−H]−).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07612099B2 |
| 출처 데이터셋 | uspto-grants-2009_11 |
| ORD ID | ord-3c0af067d68741ff8a9bf7a325a16482 |
| 출처 메모 | uspto-grants-2009_11 |