7-Methoxy-2-tetralone → 6-Methoxy-3-(4-methoxy-2-nitrophenyl)-1,2-dihydronaphthalene

HRID 1433863

반응식

HRID 1433863 반응식
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][C:9](=O)[CH2:10]2)=[CH:5][CH:4]=1.FC(F)(F)S(OC1CCC2C(=CC(OC)=CC=2)C=1)(=O)=O.C([Sn](CCCC)(CCCC)[C:39]1[CH:44]=[CH:43][C:42]([O:45][CH3:46])=[CH:41][C:40]=1[N+:47]([O-:49])=[O:48])CCC>>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6](=[CH:5][CH:4]=1)[CH2:7][CH2:8][C:9]([C:39]1[CH:44]=[CH:43][C:42]([O:45][CH3:46])=[CH:41][C:40]=1[N+:47]([O-:49])=[O:48])=[CH:10]2

참가 물질

4

반응물 3

HCID 777857-Methoxy-2-tetraloneHCID 230874467-Methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonateHCID 23087474Tributyl(4-methoxy-2-nitrophenyl)tin

생성물 1

HCID 230875356-Methoxy-3-(4-methoxy-2-nitrophenyl)-1,2-dihydronaphthalene

실험 절차

Synthesized from 7-methoxy-2-tetralone according to an analogous synthetic method to Preparation Example 82 described above, 7-methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonate (3.5 g) and tributyl(4-methoxy-2-nitrophenyl)tin (18 g) were used according to an analogous synthetic method to Preparation Example 77 to provide the title compound (1.9 g).

후처리

  1. customwere used according to an analogous synthetic method to Preparation Example 77

출처 및 근거

ORD 기록
ord-aec3a4cc0fa34e72aa5bd13c7fcc48b3
출처 데이터셋
uspto-grants-2009_11
특허 번호
US07612114B2

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