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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1433866생성일: 2026년 10월 27일

1-Bromo-4-fluoro-2-nitrobenzene → 3-(4-Fluoro-2-nitrophenyl)-7-methoxy-1,2-dihydronaphthalene

https://huagongshe.com/reaction/1433866

반응식

참여 물질

역할이름HCID투입량
반응물1-Bromo-4-fluoro-2-nitrobenzeneHCID 2773383—
반응물6-Methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonateHCID 15330256—
반응물Tributyl(4-fluoro-2-nitrophenyl)tinHCID 23087155—
생성물3-(4-Fluoro-2-nitrophenyl)-7-methoxy-1,2-dihydronaphthaleneHCID 23087411—

반응 단계

Synthesized from 1-bromo-4-fluoro-2-nitrobenzene according to an analogous synthetic method to Preparation Example 76, tributyl(4-fluoro-2-nitrophenyl)tin (7.1 g) and 6-methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonate (2.2 g) were used according to an analogous synthetic method to Preparation Example 77 to provide 3-(4-fluoro-2-nitrophenyl)-7-methoxy-1,2-dihydronaphthalene (1.4 g). The total amount of this compound was used according to an analogous synthetic method to Example 30 to provide the title compound (1.1 g).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07612114B2
출처 데이터셋uspto-grants-2009_11
ORD IDord-165de24fe0e443f090d1281e4f06cbe7
출처 메모uspto-grants-2009_11