Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Bromo-4-fluoro-2-nitrobenzene → 3-(4-Fluoro-2-nitrophenyl)-7-methoxy-1,2-dihydronaphthalene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Bromo-4-fluoro-2-nitrobenzene | HCID 2773383 | — |
| 반응물 | 6-Methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonate | HCID 15330256 | — |
| 반응물 | Tributyl(4-fluoro-2-nitrophenyl)tin | HCID 23087155 | — |
| 생성물 | 3-(4-Fluoro-2-nitrophenyl)-7-methoxy-1,2-dihydronaphthalene | HCID 23087411 | — |
반응 단계
Synthesized from 1-bromo-4-fluoro-2-nitrobenzene according to an analogous synthetic method to Preparation Example 76, tributyl(4-fluoro-2-nitrophenyl)tin (7.1 g) and 6-methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonate (2.2 g) were used according to an analogous synthetic method to Preparation Example 77 to provide 3-(4-fluoro-2-nitrophenyl)-7-methoxy-1,2-dihydronaphthalene (1.4 g). The total amount of this compound was used according to an analogous synthetic method to Example 30 to provide the title compound (1.1 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07612114B2 |
| 출처 데이터셋 | uspto-grants-2009_11 |
| ORD ID | ord-165de24fe0e443f090d1281e4f06cbe7 |
| 출처 메모 | uspto-grants-2009_11 |