Pivalic acid 6-(2-ethylamino-4,5-dimethoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-yl ester → HCID 9937238, 화합물
반응식
[CH2:1]([NH:3][C:4]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:13])=[CH:6][C:5]=1[CH:14]1[CH2:23][CH2:22][C:21]2[CH:20]=[C:19]([O:24]C(=O)C(C)(C)C)[CH:18]=[CH:17][C:16]=2[CH2:15]1)[CH3:2].Cl.[N:32]1([CH2:39][CH2:40][C:41]2[CH:42]=[CH:43][C:44]([C:47](Cl)=O)=[N:45][CH:46]=2)[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33]1>>[N:32]1([CH2:39][CH2:40][C:41]2[CH:42]=[CH:43][C:44]([CH2:47][N:3]([CH2:1][CH3:2])[C:4]3[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:13])=[CH:6][C:5]=3[CH:14]3[CH2:23][CH2:22][C:21]4[CH:20]=[C:19]([OH:24])[CH:18]=[CH:17][C:16]=4[CH2:15]3)=[N:45][CH:46]=2)[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]1참가 물질
3
실험 절차
Synthesized from pivalic acid 6-(2-ethylamino-4,5-dimethoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-yl ester (40 mg) and 5-(2-azepan-1-ylethyl)pyridine-2-carbonyl chloride hydrochloride (320 mg) according to an analogous synthetic method to Example 152, the title compound (10 mg) was obtained.
출처 및 근거
- ORD 기록
- ord-00660c7b0ecf4c4f8756e4e2b9857f4a
- 출처 데이터셋
- uspto-grants-2009_11