Benzyl Alcohol → Benzyl 4-carboxyphenylacetate

HRID 1434461노트

반응식

HRID 1434461 반응식
C(C1C=CC(CC(O)=O)=CC=1)=[O:2].C(O)C1C=CC=CC=1.[CH:21]([C:23]1[CH:28]=[CH:27][C:26]([CH2:29][C:30]([O:32][CH2:33][C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)=[O:31])=[CH:25][CH:24]=1)=[O:22]>>[CH2:33]([O:32][C:30]([CH2:29][C:26]1[CH:25]=[CH:24][C:23]([C:21]([OH:2])=[O:22])=[CH:28][CH:27]=1)=[O:31])[C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1

참가 물질

4

반응물 3

HCID 244Benzyl AlcoholHCID 113441872-(4-formylphenyl)acetic AcidHCID 19966221Benzyl 2-(4-formylphenyl)acetate

생성물 1

HCID 19966080Benzyl 4-carboxyphenylacetate수율 80.6%

실험 절차

Synthesized from (4-formylphenyl)acetic acid (1 g) and benzyl alcohol (730 mg) according to an analogous synthetic method to Example 806, benzyl (4-formylphenyl)acetate (1.4 g) was used according to an analogous synthetic method to Preparation Example 53 to provide the title compound (1.2 g).

후처리

  1. customwas used according to an analogous synthetic method to Preparation Example 53

출처 및 근거

ORD 기록
ord-0dcf9ef6c13040879ab69e788806e3d1
출처 데이터셋
uspto-grants-2009_11
특허 번호
US07612114B2

반응 노트

불러오는 중…