Water → Ethyl 2-mercapto-2-methylpropionate
반응식
Br[C:2]([CH3:9])([CH3:8])[C:3]([O:5][CH2:6][CH3:7])=[O:4].O.[SH-:11].[Na+].O>C(O)C>[CH2:6]([O:5][C:3](=[O:4])[C:2]([SH:11])([CH3:9])[CH3:8])[CH3:7]참가 물질
5
실험 절차
Ethyl 2-bromoisobutyrate (48.8 g, 0.250 mole), sodium hydrosulfide hydrate (84 g, 1.5 mole), water (100 mL), ethyl alcohol (200 mL). Let reaction mix stir at room temperature. Next day, no starting material observed. Crude yield: 74.3%; distillation yield: 36.0%.
후처리
- customreaction
- additionmix
- distillationdistillation yield: 36.0%
출처 및 근거
- ORD 기록
- ord-e75733b00fb949a88f3a90873c089504
- 출처 데이터셋
- uspto-grants-2009_11
- 특허 번호
- US07615661B2
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