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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1435211생성일: 2026년 10월 26일

N,N-Diethylglycine → 1-[4-[4-Amino-5-(5-fluoro-2-methoxy-benzoyl)-pyrimidin-2-ylamino]-piperidin-1-yl]-2-diethylamino-ethanone

https://huagongshe.com/reaction/1435211

반응식

참여 물질

역할이름HCID투입량
반응물N,N-DiethylglycineHCID 74151—
반응물[4-Amino-2-(piperidin4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone trifluoroacetic acid saltHCID 21070627—
생성물1-[4-[4-Amino-5-(5-fluoro-2-methoxy-benzoyl)-pyrimidin-2-ylamino]-piperidin-1-yl]-2-diethylamino-ethanoneHCID 9981580—

반응 단계

The same procedure as described in Example 81 was used, starting from [4-amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone trifluoroacetic acid salt, Example 59, and N,N-diethylaminoacetic acid (Aldrich) to give 1-[4-[4-amino-5-(5-fluoro-2-methoxy-benzoyl)-pyrimidin-2-ylamino]-piperidin-1-yl]-2-diethylamino-ethanone. MS (M+H)+: 459.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07615634B2
출처 데이터셋uspto-grants-2009_11
ORD IDord-4372c3a694ab448d8dc8056a61b8f746
출처 메모uspto-grants-2009_11