HCID 21070648, 화합물 → HCID 21070645, 화합물

HRID 1435351노트

반응식

HRID 1435351 반응식
[N:1]([CH:4]1[CH2:9][CH2:8][N:7]([S:10]([CH3:13])(=[O:12])=[O:11])[CH2:6][CH:5]1[O:14][CH3:15])=[N+]=[N-]>C(O)C.[Pd]>[CH3:13][S:10]([N:7]1[CH2:8][CH2:9][CH:4]([NH2:1])[CH:5]([O:14][CH3:15])[CH2:6]1)(=[O:12])=[O:11]

참가 물질

4

반응물 1

HCID 21070648HCID 21070648, 화합물

생성물 1

HCID 21070645HCID 21070645, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

The azide (270 mg, 1.15 mmol, Example 311) in ethanol was hydrogenated at 40 psi under the catalysis of palladium on carbon for 1 hour. The mixture was filtered and the filtrate was concentrated to give an off-white solid. 230 mg, 96%. It was used directly for the next step.

후처리

  1. filtrationThe mixture was filtered
  2. concentrationthe filtrate was concentrated
  3. customto give an off-white solid

출처 및 근거

ORD 기록
ord-2e7fe760fbc7439a9e7207f649dcd261
출처 데이터셋
uspto-grants-2009_11
특허 번호
US07615634B2

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