4-Thiazoleacetic acid, 2-amino-, ethyl ester → Ethyl [2-({[4-(trifluoromethyl)phenyl]sulfonyl}amino)-1,3-thiazol-4-yl]acetate

참여 물질

역할	이름	HCID	투입량
반응물	4-Thiazoleacetic acid, 2-amino-, ethyl ester	HCID 104454	—
반응물	4-(Trifluoromethyl)benzenesulfonyl chloride	HCID 2777399	—
생성물	Ethyl [2-({[4-(trifluoromethyl)phenyl]sulfonyl}amino)-1,3-thiazol-4-yl]acetate	HCID 2814007	—

반응 단계

The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 4-trifluoromethylbenzenesulfonyl chloride according to METHOD A, giving 0.14 g (33%) of an off-white solid after recrystallization from acetone/ether/petroleum ether: mp 174° C.; MS (Ionspray, [M+H]+) m/z 395; Anal. Calcd (found) for C14H13F3N2O4S2: C, 42.6 (42.4)%, H, 3.3 (2.8)%, N, 7.1 (6.8)%

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07618961B2
출처 데이터셋	uspto-grants-2009_11
ORD ID	ord-f7fa9f1e3ccc4fcfacbb9d2fa9059ea9
출처 메모	uspto-grants-2009_11