Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Thiazoleacetic acid, 2-amino-, ethyl ester → Ethyl (2-{[(4-bromo-2,5-difluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Thiazoleacetic acid, 2-amino-, ethyl ester | HCID 104454 | — |
| 반응물 | 4-Bromo-2,5-difluorobenzenesulfonyl Chloride | HCID 574590 | — |
| 생성물 | Ethyl (2-{[(4-bromo-2,5-difluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate | HCID 10275050 | — |
반응 단계
The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 4-bromo-2,5-difluorobenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (21.9 mg) with purity >90%. MS (pos) m/z 441.0, 443.0.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07618961B2 |
| 출처 데이터셋 | uspto-grants-2009_11 |
| ORD ID | ord-15fe492acbe34b05979d10fa7f3cc722 |
| 출처 메모 | uspto-grants-2009_11 |