Hydrochloric Acid → (1-Ethoxycarbonylcyclopropyl)azanium chloride

참여 물질

반응 단계

A saturated solution of HCl in ethyl acetate (20 mL) was added under nitrogen to a solution of 1-[[(1,1-dimethylethoxy)carbonyl]amino]cyclopropane carboxylic acid ethyl ester (10.07 g, 43.9 mmol), prepared in the previous step, in 20 mL of ethyl acetate at room temperature. After the addition, the reaction was stirred at room temperature for 1 h. The solid present was collected by filtration, rinsed with ethyl acetate and dried under reduced pressure to give 1-ethoxycarbonyl-cyclopropyl-ammonium chloride as a white solid.

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