Tetrahydrofuran → 2-(3,5-Bis-trifluoromethyl-phenyl)-3-(2,4-dichloro-pyrimidin-5-yl)-propionic acid methyl ester

HRID 143647

반응식

[CH2:11]([Li:12])[CH2:13][CH2:14][CH3:15].[CH3:16][O:17][C:18]([CH2:19][c:20]1[cH:21][c:22]([C:30]([F:31])([F:32])[F:33])[cH:23][c:24]([C:26]([F:27])([F:28])[F:29])[cH:25]1)=[O:34].[CH3:50][CH2:51][O:52][C:53](=[O:54])[CH3:55].[CH:1]([NH:2][CH:3]1[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]1)([CH3:9])[CH3:10].[Cl:35][c:36]1[n:37][cH:38][c:39]([CH2:43][I:44])[c:40]([Cl:42])[n:41]1.[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1>>[CH3:16][O:17][C:18]([CH:19]([c:20]1[cH:21][c:22]([C:30]([F:31])([F:32])[F:33])[cH:23][c:24]([C:26]([F:27])([F:28])[F:29])[cH:25]1)[CH2:43][c:39]1[cH:38][n:37][c:36]([Cl:35])[n:41][c:40]1[Cl:42])=[O:34]