2-Ethenyl-5-nitropyridine → 6-Ethylpyridin-3-amine

HRID 1437216노트

반응식

HRID 1437216 반응식
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([CH:10]=[CH2:11])=[N:8][CH:9]=1)([O-])=O.[H][H]>C(O)C.[C].[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([CH2:10][CH3:11])=[N:8][CH:9]=1

참가 물질

5

반응물 2

HCID 230905502-Ethenyl-5-nitropyridineHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 138607296-Ethylpyridin-3-amine

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

10% Palladium-carbon (50% wet, 90 mg) was added to 5-nitro-2-vinylpyridine (450 mg) in ethanol (30 mL), followed by stirring in a hydrogen atmosphere at room temperature for 15 hours. The catalyst was removed from the reaction mixture by filtration. Subsequently, the solvent was evaporated under reduced pressure, to thereby give the title compound as an oily substance (359 mg, 98%).

후처리

  1. customThe catalyst was removed from the reaction mixture by filtration
  2. customSubsequently, the solvent was evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-a416115830cf4a28b2528ea5ae593b4e
출처 데이터셋
uspto-grants-2009_11
특허 번호
US07622471B2

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