1-Methylimidazole → HCID 67047038, 화합물

HRID 1438377노트

반응식

HRID 1438377 반응식
[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][C:7]([C:10](=[O:12])[CH3:11])=[CH:6][CH:5]=1)=[CH2:3].CN1C=CN=C1.[N+](=[CH:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])=[N-]>C1(C)C=CC=CC=1>[C:10]([C:7]1[CH:8]=[CH:9][C:4]([C:2]2([CH3:3])[CH2:1][CH:21]2[C:22]([O:24][CH2:25][CH3:26])=[O:23])=[CH:5][CH:6]=1)(=[O:12])[CH3:11]

참가 물질

5

반응물 3

HCID 13901-MethylimidazoleHCID 12192Ethyl diazoacetateHCID 589438p-Isopropenylacetophenone

생성물 1

HCID 67047038HCID 67047038, 화합물수율 22%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

To a stirred solution of 1-[4-(1-methylethenyl)phenyl]ethanone (711 mg, 4.44 mmol, trans) (Org. Lett., 2002, 4(1), 107-109), N-methylimidazole (1.06 ml, 13.3 mmol) and Co(TPP)(89 mg, 0.13 mmol) in toluene (10 ml) was added ethyl diazoacetate (0.65 ml, 6.21 mmol) in one portion at ambient temperature. The same procedure as described in Example 2H was performed to give the title compound (236 mg, 22%) as dark yellow oil.

출처 및 근거

ORD 기록
ord-7796ae0273e245e8be2c30502ab330d1
출처 데이터셋
uspto-grants-2009_11
특허 번호
US07622589B2

반응 노트

불러오는 중…