Methanol → HCID 136354592, 화합물

HRID 1438695노트

반응식

HRID 1438695 반응식
OC1[C:3]2[CH:14]=[CH:13][CH:12]=[CH:11][C:4]=2[S:5][C:6]=1[C:7](=[NH:10])OC.[CH3:15][OH:16].[CH:17]([OH:20])([CH3:19])[CH3:18]>>[OH:16][C:15]1[C:3]2[CH:14]=[CH:13][CH:12]=[CH:11][C:4]=2[S:5][C:6]=1[C:7](=[NH:10])[O:20][CH:17]([CH3:19])[CH3:18]

참가 물질

4

반응물 3

HCID 887MethanolHCID 3776IsopropanolHCID 304079852947-34-9

생성물 1

HCID 136354592HCID 136354592, 화합물

실험 절차

20 g of methyl 3-hydroxy-benzo[b] thiophene-2-carboximidate (Example 1) are heated under reflux in 500 ml of isopropanol for three days. The methanol being formed is constantly distilled off by passing through a stream of nitrogen. Evaporation to dryness and recrystallization of the residue from ethyl acetate yields yellow crystals with an m.p. of 208° C.

후처리

  1. distillationis constantly distilled off
  2. customEvaporation
  3. customto dryness and recrystallization of the residue from ethyl acetate
  4. customyields yellow crystals with an m.p. of 208° C.

출처 및 근거

ORD 기록
ord-aa17a417dc48429283d11be6c1334e15
출처 데이터셋
uspto-grants-1977_11
특허 번호
US04056526

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