p-Toluenesulfonic acid → HCID 53642864, 화합물

HRID 1438699노트

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HRID 1438699 반응식
[CH3:1][N:2]1[C:7](=[O:8])[NH:6][CH:5]([S:9][CH3:10])[N:4]([N:11]=C(C)C)[C:3]1=[O:15].C1(C)C=CC(S(O)(=O)=O)=CC=1>C(O)C>[CH3:1][N:2]1[C:7](=[O:8])[NH:6][CH:5]([S:9][CH3:10])[N:4]([NH2:11])[C:3]1=[O:15]

참가 물질

4

반응물 2

HCID 6101p-Toluenesulfonic acidHCID 53804495HCID 53804495, 화합물

생성물 1

HCID 53642864HCID 53642864, 화합물수율 96%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

22.8 g (0.1 mole) of 1-methyl-3-isopropylideneamino-4-methylmercapto-tetrahydro-1,3,5-triazine-2,6-dione (prepared according to Example 1) were dissolved in 250 ml of ethanol and warmed, with addition of a pinch of p-toluene-sulphonic acid, for 5 hours to 50° C, whilst applying a vacuum of about 200 mm Hg. The mixture was evaporated in vacuo and the residue was recrystallized from ethanol. 18 g (96%) of 1-methyl3-amino-4-methylmercapto-tetrahydro-1,3,5-triazine-2,6-dione were obtained as colorless needles; melting point 174°-175° C.

후처리

  1. customThe mixture was evaporated in vacuo
  2. customthe residue was recrystallized from ethanol

출처 및 근거

ORD 기록
ord-9d499fb7000b4a3bbae9377699672e6d
출처 데이터셋
uspto-grants-1977_11
특허 번호
US04056527

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