Phenylglyoxylic acid hydrazide-2-acetylhydrazone → Metamitron
반응식
[C:1]([NH:4][N:5]=[C:6]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:7]([NH:9][NH2:10])=[O:8])(=O)[CH3:2]>C(O)C>[NH2:10][N:9]1[C:7](=[O:8])[C:6]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[N:5][N:4]=[C:1]1[CH3:2]참가 물질
3
실험 절차
175 g (0.8 mol) of phenylglyoxylic acid hydrazide-2-acetylhydrazone were dissolved in 2 liters of ethanol and the solution was heated to boil under reflux for 12 hours. After cooling, the product which had precipitated was filtered off. The mother liquor was partially freed from the solvent; on cooling, a further precipitate was obtained, which was also filtered off and well washed with water. The combined precipitates were dried. 123 g (76% of theory) of 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5-(4H)-one of melting point 160°-163° C. were obtained.
후처리
- temperaturethe solution was heated
- temperatureunder reflux for 12 hours
- temperatureAfter cooling
- customthe product which had precipitated
- filtrationwas filtered off
- temperatureon cooling
- customa further precipitate was obtained
- filtrationwhich was also filtered off
- washwell washed with water
- customThe combined precipitates
- customwere dried
출처 및 근거
- ORD 기록
- ord-c5c3933913bb454cb9391e076d8b65e9
- 출처 데이터셋
- uspto-grants-1977_11
- 특허 번호
- US04057546
반응 노트
불러오는 중…