Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thiocyanic Acid → 2-Imino-3-(2'-hydroxy-2'-phenylethyl)thiazolidine thiocyanate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thiocyanic Acid | HCID 781 | — |
| 반응물 | 1-Aziridineethanol, alpha-phenyl- | HCID 28834 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 2-Imino-3-(2'-hydroxy-2'-phenylethyl)thiazolidine thiocyanate | HCID 86735207 | 96% |
반응 단계
A solution of 1-hydroxy-1-phenyl-2-ethyleniminoethane (16.3 g) in dioxan (35 ml) was added dropwise and with stirring at 0° C to an aqueous solution of thiocyanic acid (200 ml of 1N solution). After the addition the mixture was stirred in the cold for 1 hour. It was then heated under reflux for 1 hour and the solution cooled. The desired compound crystallised in 96% yield, m.p. 160° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04059588 |
| 출처 데이터셋 | uspto-grants-1977_11 |
| ORD ID | ord-02459d4d0d8944cc95342dd3830824a8 |
| 출처 메모 | uspto-grants-1977_11 |