Heptanoate → 7-[2-(3(S)-Hydroxyoctyl)-4-oxo-3thiazolidinyl]heptanoic Acid

HRID 1439403

반응식

HRID 1439403 반응식
C([O:4][CH:5]([CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH2:6][CH2:7][CH:8]1[N:12]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([O:21]C)=[O:20])[C:11](=[O:23])[CH2:10][S:9]1)(=O)C.C([O-])(=O)CCCCCC>>[OH:4][C@@H:5]([CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH2:6][CH2:7][CH:8]1[N:12]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([OH:21])=[O:20])[C:11](=[O:23])[CH2:10][S:9]1

참가 물질

3

반응물 2

HCID 93052HeptanoateHCID 20317394Methyl 7-[2-(3-acetyloxyoctyl)-4-oxo-3-thiazolidinyl]heptanoate

생성물 1

HCID 228002507-[2-(3(S)-Hydroxyoctyl)-4-oxo-3thiazolidinyl]heptanoic Acid

실험 절차

This compound is prepared exactly by the same method as described in Example 1, Step B, except that the methyl 7-[2-(3-acetyloxyoctyl)-4-oxo-3-thiazolidinyl]-heptanoate is replaced by methyl 7-[2-3(S)-acetyloxyoctyl)-4-oxo-3-thiazolidinyl]heptanoate. Purification of the product resulting from this method by column chromatography on silica gel affords the pure title compound as a pale yellow oil.

후처리

  1. customThis compound is prepared exactly by the same method
  2. customPurification of the product
  3. customresulting from this method by column chromatography on silica gel

출처 및 근거

ORD 기록
ord-6e09394182894ad691dbaab0e4e9be86
출처 데이터셋
uspto-grants-1977_11
특허 번호
US04059587

연결된 노트

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