Benzoyl chloride, 3,4,5-trimethoxy- → 1-Amino-3-[(1,1-dimethylethyl)(phenylmethyl)amino]propan-2-OL

HRID 1439427노트

반응식

HRID 1439427 반응식
Cl.COC1C=C(C=C(OC)C=1OC)C([NH:9][CH2:10][CH:11]([OH:25])[CH2:12][N:13]([C:21]([CH3:24])([CH3:23])[CH3:22])[CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=O.COC1C=C(C=C(OC)C=1OC)C(Cl)=O>>[NH2:9][CH2:10][CH:11]([OH:25])[CH2:12][N:13]([C:21]([CH3:23])([CH3:22])[CH3:24])[CH2:14][C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

참가 물질

3

반응물 2

HCID 78282Benzoyl chloride, 3,4,5-trimethoxy-HCID 213976361-(3,4,5-trimethoxy benzamido)-3-(N-benzyl tert-butylamino)-2-propanol hydrochloride

생성물 1

HCID 30165241-Amino-3-[(1,1-dimethylethyl)(phenylmethyl)amino]propan-2-OL수율 78%

실험 절차

1-(3,4,5-trimethoxy benzamido)-3-(N-benzyl tert-butylamino)-2-propanol hydrochloride, starting from 7.8 g (0.034 mole) of 3,4,5-trimethoxy benzoyl chloride and 8 g (0.034 mole) of 1-amino-3-(N-benzyl tert-butylamino)-2-propanol (yield 78 %).

출처 및 근거

ORD 기록
ord-677ff1ef6ddc4c7cbc917112ba88a232
출처 데이터셋
uspto-grants-1977_11
특허 번호
US04059621

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