Water → 3-(Nitro-n-butylamino)benzophenone

HRID 1439788노트

반응식

HRID 1439788 반응식
Cl[C:2]1[CH:15]=[CH:14][C:5]([C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:7])=[CH:4][C:3]=1[N+:16]([O-])=O.[CH2:19](N)[CH2:20][CH2:21][CH3:22].O.[N+:25](C1C=C(C=CC=1NCCCC)C(C1C=CC=CC=1)=O)([O-:27])=[O:26]>C1(C)C=CC=CC=1>[N+:25]([N:16]([CH2:19][CH2:20][CH2:21][CH3:22])[C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:2]=1)[C:6]([C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)=[O:7])([O-:27])=[O:26]

참가 물질

6

반응물 4

HCID 962WaterHCID 8007ButylamineHCID 417434-Chloro-3-nitrobenzophenoneHCID 6205244-n-Butylamino-3-nitrobenzophenone

생성물 1

HCID 205552293-(Nitro-n-butylamino)benzophenone

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

A mixture of 4-chloro-3-nitrobenzophenone (13.08 g.; 0.05 mole) and n-butylamine (10.97 g.; 0.15 mole) are refluxed and stirred for 4 hours. To the reaction mixture is added water (300 ml.) and toluene (200 ml.) and the toluene layer collected and dried over magnesium sulfate. The toluene solution is filtered and the toluene removed under vacuum to afford 11.4 g. of 3-nitro-4-n-butylaminobenzophenone.

후처리

  1. temperatureare refluxed
  2. customthe toluene layer collected
  3. dry with materialdried over magnesium sulfate
  4. filtrationThe toluene solution is filtered
  5. customthe toluene removed under vacuum
  6. customto afford 11.4 g

출처 및 근거

ORD 기록
ord-e97de0f6d624432391909d664805b238
출처 데이터셋
uspto-grants-1977_11
특허 번호
US04060636

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