Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Fmoc-Gly-OH → L-Phenylalanine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Fmoc-Gly-OH | HCID 93124 | — |
| 반응물 | Fmoc-phenylalanine | HCID 978331 | — |
| 반응물 | Fmoc-L-tryptophan | HCID 978343 | — |
| 반응물 | (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid | HCID 978356 | — |
| 반응물 | (2S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)hexanoic acid | HCID 7009636 | — |
| 반응물 | 4-tert-Butyl N-((9H-Fluoren-9-ylmethoxy)carbonyl)-D-aspartate | HCID 7018816 | — |
| 생성물 | L-Phenylalanine | HCID 6140 | — |
| 생성물 | L-Tryptophan | HCID 6305 | — |
| 생성물 | N-Methylphenylalanine | HCID 6951135 | — |
반응 단계
By following essentially the procedure of Table 2 and sequentially coupling Fmoc-MePhe-OH, Fmoc-DAsp(OtBu)-OH, Fmoc-Phe-OH, Fmoc-Trp-OH, Fmoc-Gly-OH, Fmoc-Ahx-OH and Hpa-OSu, the title compound was prepared. Amino Acid analysis following acid decomposition gave Asp 1.01 (1), Gly 0.99 (1), MePhe 1.06 (1), Ahx 1.02 (1), Trp 1.06 (1), Phe 0.94 (1), NH3 0.82. MS (FAB): m/e 931 (M-H)-.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05502164 |
| 출처 데이터셋 | uspto-grants-1996_03 |
| ORD ID | ord-cb08aa5f47424d19ac33ed09291c68ca |
| 출처 메모 | uspto-grants-1996_03 |