HCID 7062386, 화합물 → HCID 6930630, 화합물
반응식
[CH3:1][C@H:2]1[CH2:7][N:6]([C:8]2[CH:13]=[CH:12][C:11]([N+:14]([O-])=O)=[CH:10][CH:9]=2)[CH2:5][C@@H:4]([CH3:17])[O:3]1.[H][H]>CCO.[Pd]>[CH3:1][C@H:2]1[CH2:7][N:6]([C:8]2[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=2)[CH2:5][C@@H:4]([CH3:17])[O:3]1참가 물질
5
실험 절차
1-(Cis-2,6-dimethylmorpholino)-4-nitrobenzene (Method 18, 8 g) in EtOH (100 ml) was reduced with hydrogen over 10% palladium/carbon (800 mg) at 50° C. After filtering off the catalyst and washing with EtOH, evaporation of the filtrate gave the title compound as a red/brown oil, which started to solidify after several days (quantitative yield). NMR (CDCl3) 1.23 (d, 6H), 2.33 (t, 2H), 3.25 (d, 2H), 3.81 (m, 2 h), 6.65 (d, 2H), 6.79 (d, 2H); m/z 207.
후처리
- filtrationAfter filtering off the catalyst
- washwashing with EtOH, evaporation of the filtrate
출처 및 근거
- ORD 기록
- ord-9ba3cbe889d542be84ea9bf7ede4d81b
- 출처 데이터셋
- uspto-grants-2010_02
- 특허 번호
- US07655652B2
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