2-Methylimidazole → 4-(2-Methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzonitrile

HRID 1441742

반응식

HRID 1441742 반응식
Cl[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[C:10]([F:13])([F:12])[F:11].[CH3:14][C:15]1[NH:16][CH:17]=[CH:18][N:19]=1>>[CH3:14][C:15]1[N:16]([C:2]2[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=2[C:10]([F:13])([F:12])[F:11])[CH:17]=[CH:18][N:19]=1

참가 물질

3

실험 절차

The title compound is prepared using an analogous method as described in Example 1.1, utilising 4-chloro-3-(trifluoromethyl)-benzonitrile (Lancaster Synthesis GmbH) and 2-methyl-imidazole (Fluka, Buchs, Switzerland), with a reaction temperature of 145° C. for 38 hours.

출처 및 근거

ORD 기록
ord-147df7f93a424152b8f8e11694aed57b
출처 데이터셋
uspto-grants-2010_02
특허 번호
US07655669B2

연결된 노트

불러오는 중…