Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dextroamphetamine → Lisdexamfetamine Dimesylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dextroamphetamine | HCID 5826 | — |
| 반응물 | Amphedrine | HCID 222898 | — |
| 반응물 | L-lysine d-amphetamine | HCID 131727865 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Lisdexamfetamine Dimesylate | HCID 11597697 | — |
반응 단계
Male Sprague-Dawley rats were provided water ad libitum, fasted overnight, and dosed by oral gavage with 1.5, 3, 6, 12, and 60 mg/kg of amphetamine sulfate or L-lysine-d-amphetamine containing the equivalent amounts of d-amphetamine. Concentrations of d-amphetamine were measured by ELISA.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07659253B2 |
| 출처 데이터셋 | uspto-grants-2010_02 |
| ORD ID | ord-be634dd2ffce4a8598c4c234fbe793f6 |
| 출처 메모 | uspto-grants-2010_02 |