Ammonia → 5-Nitro-1,2-dihydroisoquinolin-1-one

HRID 1443280노트

반응식

HRID 1443280 반응식
[N+:1]([C:4]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:5]=1[CH:6]=[CH:7][O:8][C:9]2=O)([O-:3])=[O:2].[NH3:15]>C(O)C>[N+:1]([C:4]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:5]=1[CH:6]=[CH:7][NH:15][C:9]2=[O:8])([O-:3])=[O:2]

참가 물질

4

반응물 2

HCID 222AmmoniaHCID 100127605-nitro-1H-isochromen-1-one

생성물 1

HCID 2313785-Nitro-1,2-dihydroisoquinolin-1-one수율 79.7%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

2.51 g (13.13 mmol) of 5-nitroisocoumarin is added in 100 ml of ethanol. Ammonia is pressure-forced in in an autoclave. The product precipitates and is suctioned off. 1.98 g (79.7%) of the desired compound is isolated.

후처리

  1. customThe product precipitates

출처 및 근거

ORD 기록
ord-e356d8ae807e416bb4653acdbcf1ac99
출처 데이터셋
uspto-grants-2010_02
특허 번호
US07659297B2

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