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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1443367생성일: 2026년 10월 26일

6-Bromopyridine-2-carboxamide → 6-[2-(2,4-Dichloro-benzoyl)-3-methyl-benzofuran-6-yl]-pyridine-2-carboxylic acid amide

https://huagongshe.com/reaction/1443367

반응식

참여 물질

역할이름HCID투입량
반응물6-Bromopyridine-2-carboxamideHCID 21961408—
반응물(2,4-Dichlorophenyl)-[3-methyl-6-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-benzofuran-2-yl]-methanoneHCID 59788883—
생성물6-[2-(2,4-Dichloro-benzoyl)-3-methyl-benzofuran-6-yl]-pyridine-2-carboxylic acid amideHCID 59788885—

반응 단계

6-[2-(2,4-Dichloro-benzoyl)-3-methyl-benzofuran-6-yl]-pyridine-2-carboxylic acid amide was prepared via a Suzuki coupling of ((2,4-dichlorophenyl)-[3-methyl-6-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-benzofuran-2-yl]-methanone and 6-Bromo-pyridine-2-carboxylic acid amide as described in method 6 step 2. 1H-NMR (CD3OD) δ 8.42 (s, 1H), 8.23-8.17 (m, 2H), 8.09-8.02 (m, 2H), 7.92 (d, J=8 Hz 1H), 7.64 (d, J=2 Hz, 1H), 7.58-7.51 (m, 2H), 2.64 (s, 3H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07659412B2
출처 데이터셋uspto-grants-2010_02
ORD IDord-f077ea3f0f434bd3a96c82e6c61fbf06
출처 메모uspto-grants-2010_02