6-[4-(2-Amino-phenyl)-oxazol-2-yl]-hexanoic acid ethyl ester → 6-[4-(2-Amino-phenyl)-oxazol-2-yl]-hexanoic acid
반응식
NC1C=CC=CC=1C1N=C(CCCC(O)=O)OC=1.C([O:21][C:22](=[O:40])[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]1[O:29][CH:30]=[C:31]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=2[NH2:39])[N:32]=1)C>>[NH2:39][C:34]1[CH:35]=[CH:36][CH:37]=[CH:38][C:33]=1[C:31]1[N:32]=[C:28]([CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][C:22]([OH:40])=[O:21])[O:29][CH:30]=1참가 물질
3
실험 절차
Using a method similar to the procedure described for the preparation of 4-[4-(2-amino-phenyl)-oxazol-2-yl]-butyric acid; hydrolysis of 6-[4-(2-amino-phenyl)-oxazol-2-yl]-hexanoic acid ethyl ester (2.7 g, 8.9 mmol) gives 6-[4-(2-amino-phenyl)-oxazol-2-yl]-hexanoic acid (2.03 g, 83%). MS (ES): (M+1)+ 274.9 m/z.
출처 및 근거
- ORD 기록
- ord-fb4b2e0d9e0241fa9dcda8a82a587b69
- 출처 데이터셋
- uspto-grants-2010_02