Aniline → (-)-1-(1-Phenyl-2-propenyl)phenylamine

반응식

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(=O)(O[CH2:12][CH:13]=[CH:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)OC>>[C:15]1([CH:14]([C:2]2([NH2:1])[CH:7]=[CH:6][CH:5]=[CH:4][CH2:3]2)[CH:13]=[CH2:12])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

참가 물질

반응물 2

HCID 6115Aniline

HCID 54135828Methyl 3-phenylprop-2-en-1-yl carbonate

생성물 1

HCID 68584977(-)-1-(1-Phenyl-2-propenyl)phenylamine

실험 절차

By the procedure with [(COD)IrCl]2 (6.7 mg, 0.010 mmol) and L1 (Sa,Sc,Sc) (10.8 mg, 0.020 mmol) the reaction of aniline (130 mg, 1.40 mmol) and methyl cinnamyl carbonate (188 mg, 0.980 mmol) was conducted at room temperature for 24 h. 1H NMR and GC analysis of the crude reaction mixture showed that the conversion of the reaction was less than 1%.

후처리

custom1H NMR and GC analysis of the crude reaction mixture

출처 및 근거

ORD 기록: ord-2100cafdb4bd4016aca38deed8f67b56
출처 데이터셋: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07732365B2

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