Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(R)-3-Methylmorpholine → 4-[4-(4-Fluoro-phenyl)-6-(2-methyl-piperazin-1-yl)-pyrimidin-2-yl]-3-methyl-morpholine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (R)-3-Methylmorpholine | HCID 641498 | — |
| 반응물 | 4-(4-Fluoro-phenyl)-6-(2-methyl-piperazin-1-yl)-2-(2-methyl-pyrrolidin-1-yl)-pyrimidine | HCID 66838863 | — |
| 생성물 | 4-[4-(4-Fluoro-phenyl)-6-(2-methyl-piperazin-1-yl)-pyrimidin-2-yl]-3-methyl-morpholine | HCID 66838893 | — |
반응 단계
This compound is prepared using (R)-3-methylmorpholine (WO 02/064096) in a procedure analogous to that used for the preparation of 4-(4-fluoro-phenyl)-6-(2-methyl-piperazin-1-yl)-2-(2-methyl-pyrrolidin-1-yl)-pyrimidine in Example 2F step 3.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07662830B2 |
| 출처 데이터셋 | uspto-grants-2010_02 |
| ORD ID | ord-eb800fe207aa4d26b4a2d0b7a41f0bc5 |
| 출처 메모 | uspto-grants-2010_02 |