Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Aminocinnamic acid ethyl ester → 3-(3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenyl)-acrylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Aminocinnamic acid ethyl ester | HCID 97825 | — |
| 반응물 | 5-(3-Chlorophenyl)furan-2-carboxylic acid | HCID 736256 | — |
| 생성물 | 3-(3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenyl)-acrylic acid ethyl ester | HCID 68490796 | — |
반응 단계
Carboxylic acid (65) (58 mg, 0.26 mmol) was coupled to ethyl ester (60) (50 mg, 0.26 mmol) using Method C. The crude residue was purified by column chromatography eluting with a stepped gradient of 10-15% EtOAc in heptane to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07662839B2 |
| 출처 데이터셋 | uspto-grants-2010_02 |
| ORD ID | ord-57635100a5f04ce58e90eeb35e11ad1a |
| 출처 메모 | uspto-grants-2010_02 |