5-Bromo-2-furanecarboxylic acid → 5-(4-Fluorophenyl)furan-2-carboxylic acid

HRID 1444276

반응식

HRID 1444276 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5](B(O)O)=[CH:4][CH:3]=1.Br[C:12]1[O:16][C:15]([C:17]([OH:19])=[O:18])=[CH:14][CH:13]=1>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:12]2[O:16][C:15]([C:17]([OH:19])=[O:18])=[CH:14][CH:13]=2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 685115-Bromo-2-furanecarboxylic acidHCID 2856454-Fluorophenylboronic acid

생성물 1

HCID 7389915-(4-Fluorophenyl)furan-2-carboxylic acid

실험 절차

4-Fluoro-phenylboronic acid (611 mg, 4.4 mmol) was coupled to 5-bromo-2-furoic acid (1 g, 4.8 mmol) using Method F to give the title compound.

출처 및 근거

ORD 기록
ord-b3e49067fc4640208a6463b45f00aa2f
출처 데이터셋
uspto-grants-2010_02
특허 번호
US07662839B2

연결된 노트

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