Potassium Carbonate → diethyl 2-bromo-1-(but-2-ynyl)-1H-imidazole-4,5-dicarboxylate
반응식
BrC1N(CC=C(C)C)[C:4]([C:11](OC)=O)=[C:5]([C:7](OC)=O)N=1.[Br:20][C:21]1[NH:22][C:23]([C:31]([O:33][CH2:34][CH3:35])=[O:32])=[C:24]([C:26]([O:28][CH2:29][CH3:30])=[O:27])[N:25]=1.BrCC#CC.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[Br:20][C:21]1[N:25]([CH2:11][C:4]#[C:5][CH3:7])[C:24]([C:26]([O:28][CH2:29][CH3:30])=[O:27])=[C:23]([C:31]([O:33][CH2:34][CH3:35])=[O:32])[N:22]=1참가 물질
6
반응물 4
생성물 1
시약·촉매·용매 1
실험 절차
Prepared analogously to 1b from 3.50 g (12.02 mmol) diethyl 2-bromo-imidazole-4,5-dicarboxylate with 1.09 ml (12.1 mmol) 1-bromo-2-butyne and 2.07 g (15.00 mmol) potassium carbonate in 15 ml of dimethylformamide.
출처 및 근거
- ORD 기록
- ord-64dc521169de4750998c617aad232830
- 출처 데이터셋
- uspto-grants-2010_02
- 특허 번호
- US07667035B2
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