2-Methyl-6-phenyl-hexa-3,5-diyn-2-ol → Buta-1,3-diynylbenzene

HRID 1446051노트

반응식

HRID 1446051 반응식
CC(O)([C:4]#[C:5][C:6]#[C:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)C>C1(C)C=CC=CC=1>[C:7]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)#[C:6][C:5]#[CH:4]

참가 물질

3

반응물 1

HCID 40884452-Methyl-6-phenyl-hexa-3,5-diyn-2-ol

생성물 1

HCID 11355482Buta-1,3-diynylbenzene

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

A mixture of 2-methyl-6-phenyl-hexa-3,5-diyn-2-ol (3.8 g, 20.6 mmol) sodium hydride (60%, 83 mg, 2.06 mmol) and toluene (20 ml) was stirred at reflux for 1 hour. The mixture was evaporated. Chromatography on silica gel with petroleum and ethyl acetate (3:1), gave the title compound. Yield 0.54 g (21%).

후처리

  1. temperatureat reflux for 1 hour
  2. customThe mixture was evaporated

출처 및 근거

ORD 기록
ord-46b49c79abd846b4a293276004096a17
출처 데이터셋
uspto-grants-2010_02
특허 번호
US07667040B2

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