Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
n-Methyl-p-aminophenol → 4-[N-methyl-N-(2-benzimidazolyl)amino]phenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | n-Methyl-p-aminophenol | HCID 5931 | — |
| 반응물 | 2-Chlorobenzimidazole | HCID 78572 | — |
| 용매 | Acetonitrile--water (1/1) | HCID 18373917 | — |
| 생성물 | 4-[N-methyl-N-(2-benzimidazolyl)amino]phenol | HCID 13314818 | 58.7% |
반응 단계
A mixture of 2-chlorobenzimidazole (1.0 g), 4-(N-methylamino)phenol (1.13 g) and acetonitrile/water (1:1) was heated under reflux for a period of 5 hours. The mixture was concentrated, made basic with dilute ammonium hydroxide and the solid was collected. The product was recrystallised from ethanol to give 4-[N-methyl-N-(2-benzimidazolyl)amino]phenol (0.92 g) as colourless crystals, mp>260° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04314065 |
| 출처 데이터셋 | uspto-grants-1982_02 |
| ORD ID | ord-fac870d124ac453eb09f7b0f90d47b6a |
| 출처 메모 | uspto-grants-1982_02 |