Potassium Carbonate → 2-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-(phenylmethyl)-1H-imidazole

HRID 1447029노트

반응식

HRID 1447029 반응식
Cl.[CH2:2]([N:9]1[CH:13]=[CH:12][N:11]=[C:10]1[CH2:14][CH:15]1[O:20][C:19]2[CH:21]=[CH:22][CH:23]=[CH:24][C:18]=2[O:17][CH2:16]1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C(=O)([O-])[O-].[K+].[K+]>CCOCC>[CH2:2]([N:9]1[CH:13]=[CH:12][N:11]=[C:10]1[CH2:14][CH:15]1[O:20][C:19]2[CH:21]=[CH:22][CH:23]=[CH:24][C:18]=2[O:17][CH2:16]1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

참가 물질

4

반응물 2

HCID 11430Potassium CarbonateHCID 12761772HCID 12761772, 화합물

생성물 1

HCID 127617712-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-(phenylmethyl)-1H-imidazole

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

1-Benzyl-2-(1,4-benzodioxan-2-ylmethyl)imidazole hydrochloride (1.0 g) suspended in 50 ml of ether is stirred with excess dilute aqueous potassium carbonate solution until the salt is completely dissolved. The organic layer is then separated, washed twice with water, dried over magnesium sulfate and evaporated to yield 1-benzyl-2-(1,4-benzodioxan-2-ylmethyl)imidazole.

후처리

  1. dissolutionis completely dissolved
  2. customThe organic layer is then separated
  3. washwashed twice with water
  4. dry with materialdried over magnesium sulfate
  5. customevaporated

출처 및 근거

ORD 기록
ord-98be6c1b3304495fa9b0c0fe1730be3a
출처 데이터셋
uspto-grants-1982_02
특허 번호
US04315021

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