Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Amino-5-hydroxy-1,7-naphthalenedisulfonic acid → 5-Hydroxy-4-(5-nitro-o-toluamido)-1,7-naphthalenedisulfonic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Amino-5-hydroxy-1,7-naphthalenedisulfonic acid | HCID 67224 | — |
| 반응물 | 2-Methyl-5-nitrobenzoyl chloride | HCID 4436568 | — |
| 반응물 | Sodium Acetate Trihydrate | HCID 23665404 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 5-Hydroxy-4-(5-nitro-o-toluamido)-1,7-naphthalenedisulfonic acid | HCID 56996136 | — |
반응 단계
A 16 g portion of 4-amino-5-hydroxy-1,7-naphthalenedisulfonic acid in 120 ml of water is adjusted to pH 7.2. A 7.6 g portion of sodium acetate trihydrate and 8.8 g of 2-methyl-5-nitrobenzoyl chloride are added with vigorous stirring. The mixture is stirred overnight at room temperature. The solid is then collected by filtration, washed with water, 80% ethanol, ethanol, ether and dried, giving 13.0 g of 5-hydroxy-4-(5-nitro-o-toluamido)-1,7-naphthalenedisulfonic acid, disodium salt.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04177209 |
| 출처 데이터셋 | uspto-grants-1979_12 |
| ORD ID | ord-be3ba39cee73474a88dd685af3dbaf10 |
| 출처 메모 | uspto-grants-1979_12 |