Potassium Hydroxide → HCID 54394348, 화합물

HRID 1447603노트

반응식

HRID 1447603 반응식
[CH3:1][O:2][C:3]([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([S:14][C:15]3[CH:20]=[CH:19][C:18]([O:21]C(=O)C)=[CH:17][CH:16]=3)=[CH:10][N:9]2[CH:25]=1)=[O:4].[OH-].[K+]>CO.O>[CH3:1][O:2][C:3]([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([S:14][C:15]3[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][CH:16]=3)=[CH:10][N:9]2[CH:25]=1)=[O:4]

참가 물질

4

반응물 2

HCID 14797Potassium HydroxideHCID 53698142HCID 53698142, 화합물

생성물 1

HCID 54394348HCID 54394348, 화합물

시약·촉매·용매 1

HCID 22242641Methanol--water (1/1)용매

실험 절차

1.0 Gm. of the acetate derivative obtained in Example 15 is heated with a 10 ml. 50% methanol-water solution of 0.5 g. of potassium hydroxide for one hour. After evaporation of the methanol in vacuo the reaction mixture is acidified with glacial acetic acid. The resultant solids are removed by filtration, washed with water and dried to yield 2-(methoxycarbonylamino) 6-(p-hydroxyphenylthio) imidazo [1,2-a] pyridine.

후처리

  1. customAfter evaporation of the methanol in vacuo the reaction mixture
  2. customThe resultant solids are removed by filtration
  3. washwashed with water
  4. customdried

출처 및 근거

ORD 기록
ord-210d659c43c74d5ca02ae2bd7e02eeff
출처 데이터셋
uspto-grants-1979_12
특허 번호
US04177274

반응 노트

불러오는 중…