Acetate-hydrochloric acid → 7-(m-Carboxyphenyl)pyrazolo[1,5-a]pyrimidine
반응식
[C:1]([C:3]1[CH:4]=[C:5]([C:9]2[N:14]3[N:15]=[CH:16][CH:17]=[C:13]3[N:12]=[CH:11][CH:10]=2)[CH:6]=CC=1)#N.[C:18]([OH:21])(=[O:20])[CH3:19].Cl>>[C:18]([C:19]1[CH:6]=[C:5]([C:9]2[N:14]3[N:15]=[CH:16][CH:17]=[C:13]3[N:12]=[CH:11][CH:10]=2)[CH:4]=[CH:3][CH:1]=1)([OH:21])=[O:20]참가 물질
3
실험 절차
A sample of 7-(m-cyanophenyl)pyrazolo[1,5-a]pyrimidine is heated with acetic acid-hydrochloric acid to give 7-(m-carboxyphenyl)pyrazolo[1,5-a]pyrimidine. The preceding compound is heated with sulfur tetrafluoride for 20 hours at 150° C. to give the product of the example, m.p. 104°-106° C.
출처 및 근거
- ORD 기록
- ord-267c7c7ab1b64ad8bd0c026bdbd86f14
- 출처 데이터셋
- uspto-grants-1979_12
- 특허 번호
- US04178449
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