Triethylamine → HCID 53726423, 화합물

HRID 1448078노트

반응식

HRID 1448078 반응식
[N:1](=[C:3]1[CH2:8][S:7][CH2:6][CH2:5][S:4]1)[OH:2].[CH3:9][N:10]([S:14][C:15]([CH3:22])([C:17](=[O:21])[CH:18]([CH3:20])[CH3:19])[CH3:16])[C:11](Cl)=[O:12].C(N(CC)CC)C>O1CCOCC1>[CH3:9][N:10]([S:14][C:15]([CH3:16])([C:17](=[O:21])[CH:18]([CH3:19])[CH3:20])[CH3:22])[C:11]([O:2][N:1]=[C:3]1[CH2:8][S:7][CH2:6][CH2:5][S:4]1)=[O:12]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 54024146N-methyl-N-(2,4-dimethyl-3-oxo-2-pentanesulfenyl)carbamoyl chlorideHCID 71364189N-1,4-Dithian-2-ylidenehydroxylamine

생성물 1

HCID 53726423HCID 53726423, 화합물

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

Prepared as in Example 1 by reacting 8.0 g (0.053 m) of 2-oximino-1,4-dithiane, 15.2 g (0.058 m) of N-methyl-N-(2,4-dimethyl-3-oxo-2-pentanesulfenyl)carbamoyl chloride and 5.42 g (0.053 m) of triethylamine in 100 ml of dioxane. The product crystallized from isopropyl ether-ethyl acetate to yield 4.3 g of a white solid, (m.p. 80°-82° C.) Recrystallization raised the melting point to 85°-86° C.

후처리

  1. customPrepared as in Example 1
  2. customThe product crystallized from isopropyl ether-ethyl acetate
  3. customto yield
  4. custom4.3 g of a white solid, (m.p. 80°-82° C.) Recrystallization
  5. temperatureraised the melting point to 85°-86° C.

출처 및 근거

ORD 기록
ord-b3314970f6a2492ca88cfbb8531c9eb5
출처 데이터셋
uspto-grants-1979_12
특허 번호
US04179514

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