Methyl Anthranilate → 4(1H)-Quinazolinone

HRID 1448801노트

반응식

ClC[C:3]([NH:5][C:6]1[C:7](=[CH:11][CH:12]=[CH:13][CH:14]=1)[C:8](O)=[O:9])=O.COC(=O)C1C(=CC=CC=1)[NH2:20]>>[N:5]1[C:6]2[C:7](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:8](=[O:9])[NH:20][CH:3]=1

참가 물질

반응물 2

HCID 8635Methyl Anthranilate

HCID 919916HCID 919916, 화합물

생성물 1

HCID 1354087534(1H)-Quinazolinone

실험 절차

2-Chloromethyl-3-82-methoxycarbonyl-phenyl)-4H-quinazolin-4-one (melting point: 197°-199° C., recrystallised from toluene) was prepared from N-chloroacetyl-anthranilic acid and anthranilic acid methyl ester analogously to the method in J. pr. Chem. (4) 14 (1961), 84.

출처 및 근거

ORD 기록: ord-64425e939cee4d9981aa973404cd67a6
출처 데이터셋: uspto-grants-1980_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04187306

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