Catechol → 3,4-Dihydroxybenzenesulfonic acid

HRID 1448971노트

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HRID 1448971 반응식
[C:1]1([C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4])[OH:2].[S:9](=O)(=[O:12])([OH:11])[OH:10].C(=O)([O-])[O-].[Ba+2]>>[OH:2][C:1]1[CH:8]=[C:7]([S:9]([OH:12])(=[O:11])=[O:10])[CH:6]=[CH:5][C:3]=1[OH:4]

참가 물질

4

반응물 3

HCID 289CatecholHCID 1118Sulfuric AcidHCID 10563Barium Carbonate

생성물 1

HCID 1890033,4-Dihydroxybenzenesulfonic acid

반응 조건

온도
45 °C

실험 절차

Catechol (180 g.) was added in portions to stirred sulfuric acid (138.5 ml.) so that the reaction temperature remained below 25° C. After addition was complete, the semi-solid mixture was heated at 45° C. for 60 minutes then cooled to room temperature and poured into ice-water (700 ml.). The solution was neutralized with solid barium carbonate, the barium sulfate collected, the filtrate acidified to pH 1 with concentrated sulfuric acid then refiltered. The filtrate was evaporated to leave crude 3,4-dihydroxybenzenesulfonic acid (182.40 g.) which was used without purification.

후처리

  1. customremained below 25° C
  2. additionAfter addition
  3. temperaturethen cooled to room temperature
  4. customthe barium sulfate collected
  5. customThe filtrate was evaporated

출처 및 근거

ORD 기록
ord-717b63f7914d4a838f94686c302365ef
출처 데이터셋
uspto-grants-1980_02
특허 번호
US04188390

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